downloadable Biopsy Request forms now available in PDF format!
Formalin-fixed biopsy specimens are processed as soon as they
are recieved, and the H&E sections are interpreted the next
working day. Special histochemical stains and immunohistochemical
stains carry an extra charge for each procedure. Special stains (PAS,
Iron, gram, etc) are received the day after they are ordered.
Immunohistochemical stains are completed four working days
after they are ordered. These stains are requested by the pathologist
in cases where correct diagnosis is contingent on them.
Another service feature is the use of
direct immunofluorescence (DIF) to detect the presence of
various inflammatory proteins and to confirm the diagnosis of several
mucocutaneous diseases, such as
pemphigoid and pemphigus. The tests are done on fresh,
unfixed biopsy tissue which have been stored in a special transport
medium (a DIF kit including FedEx labels will be sent promptly upon
request of the clinician. The transport medium has an expiration date,
so long-term storage is not recommended). The
tissue is sectioned frozen, sections placed on slides, then tested with
five fluorescent proteins. The procedure is
performed weekly on several specimens at once.
(Reference - Daniels T, Quadra-White
C. Direct immunofluorescence in oral mucosal disease: a diagnostic
analysis of 130 cases. Oral Surg 51:38-47, 1981)
Telephone consultations with the
pathologists regarding biopsy reports and/or patient
management are available Monday through Friday (except holidays) by
. E-mail consultations (including exchange of photo and x-ray
attachments) can also be arranged.
opinions on microscopic interpretations of tissue previously processed
and reported by other laboratories are gladly provided. The clinician
should request the outside pathologist to send the slides, blocks,
other pertinent material directly to:
Pathology, Room S-512, 513 Parnassus, University of California, San
Francisco, CA 94143-0424 . Barring any necessity of
diagnostic tests, a FAX or telephone report is available one working
day after receipt. All materials will be promptly returned.
by the UCSF Oral Pathology Diagnostic Services, all rights reserved.
Nusi.Dekker@ucsf.edu if you have questions regarding this
site. Last updated May 1, 2008.
Radiographic interpretation of jaw
lesions is also available upon request at no charge. This opinion will
include differential diagnosis and patient management suggestions if
requested by the clinician. Please send radiographs to the above
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